Peripheral intravenous catheterization (PIVC) is considered the most widely performed invasive procedure in the hospital setting. It frequently is needed for the prompt diagnosis and treatment of admitted patients (Cooke et al., 2018). PIVC is required in 70%-80% of hospitalized patients (Cooke et al., 2018; Van Loon et al.,2018) and most often is indicated for medication administration, hydration therapy, diagnostic and laboratory testing, and blood transfusion (Reeves et al., 2017; Stolz et al., 2015; Van Loon et al., 2018). Initiation of IV therapy, nonetheless, may become complicated in patients who have poor vasculature or known history of difficult venous access (DVA) (10%-24% of adults, approximately 37% of children) (Kaur et al., 2019). Patients presenting with conditions, such as diabetes, drug abuse, sickle cell anemia, obesity, and shock, may pose a significant challenge to establishingPIVC (Gottlieb et al., 2017; Heinrichs et al., 2013). Multiple PIVC attempts may be needed in patients with poor vasculature, leading to pain and discomfort. Research has documented first-attempt success rates via traditional methods at 53%-75.6% and 76%-91% for pediatric and adult populations, respectively (Heinrichs et al., 2013). Furthermore, clinical nurses have reported an average as high as 5.5 attempts per PIVC (Reeves et al., 2017). Physicians often resort to central venous catheter (CVC) insertions for cases of DVA, carrying a 5%-19% complication rate (e.g., local infection, bacteremia, thrombosis, pneumothorax) (Kaur et al., 2019; Liu et al., 2014; Rodriguez-Calero et al.,2018; Tsotsolis et al., 2015). The estimated cost of a single CVC-related infection in 2019 was
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